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Department of

 
 

STEM CELL BIOLOGY AND PHARMACOLOGY OF NEURODEGENERATIVE DISEASES  

The lab works on Huntington's Disease (HD) in order to identify the pathways affected by the disease mutation as well as the function and evolution of the normal HD gene and novel stem cell based strategies for disease modelling and experimental transplantation.


Website: http://www.cattaneolab.it/



 Elena Cattaneo

Full Professor in Pharmacology


Email: cattaneooffice@unimi.it

Phones: +39 02 503 25842

Address: Padiglione Invernizzi, IV piano ala A, Via Francesco Sforza

Website: >>>

Thesis available: >>>

External links:Scopus

Keywords: Huntington’s Disease, stem cells, genome editing/ Malattia di Huntington, cellule staminali, genome editing

Main topics of the group:

  • Stem Cells as a model of the developing human striatum in Huntington's Disease
  • Pathogenesis and evolution of Huntington gene

 



 Chiara Zuccato
 
Associate Professor in Pharmacology


Email: chiara.zuccato@unimi.it

Phones: +39 02 503 25839

Address: Padiglione Invernizzi, IV piano ala A, Via Francesco Sforza

Website: >>>

Thesis available: >>>

External links:Scopus

Keywords: Huntington's Disease, synapse, huntingtin/ Malattia di Huntington, sinapasi, huntintina

Main topics of the group:

  • Function of Huntington Gene
  • Dysfunction of cortico-striatal synapse in Huntington's Disease: the role of ADAM10

 



 Marta Valenza

Associate Professor in Pharmacology


Email: marta.valenza@unimi.it

Phones: +39 02 503 25846

Address: Padiglione Invernizzi, IV piano ala A, Via Francesco Sforza

Website: >>>

Thesis available: >>>

Keywords: Huntington’s Disease, cholesterol, nanoparticles/ Malattia di Huntington, colesterolo, nanoparticelle

Main topics of the group: Brain Cholesterol in Huntington's Disease




 Dario Besusso

Assistant Professor in Farmacologia


Email: dario.besusso@unimi.it

Phones: +39 02 503 25847

Address: Padiglione Invernizzi, IV piano ala A, Via Francesco Sforza

Website: >>>

Thesis available: >>>

KeywordsHuntington's Disease, stem cells, CRISPR/Cas9 technology/ Malattia di Huntington, cellule staminali, CRISPR/Cas9

Main topics of the group: 

  • Investigating the contribution of HTT repeat somatic instability of Huntington’s Disease
  • Development of a cell replacement approach for HD using hPSC
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